PAKISTAN JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY http://www.pjbmb.com/index.php/pjbmb <div class="fw-row"> <div class="fw-col-xs-12"> <div class="seline-default-heading"> <p>The Pakistan Journal of Biochemistry and Molecular Biology (PJBMB) (ISSN P 1681-4525; ISSN E 2788-4147) is an open-access journal that publishes papers that contribute to knowledge in the field of Biochemistry, Molecular Biology, and related areas.</p> <p>PJBMB is currently published under the auspices of Mohammad Ali Jinnah University in Karachi, Pakistan.</p> <p>An article for publication must describe substantial original research undertaken according to the scope of this journal. A manuscript submitted for publication implies that the work described has not been published before (except as an abstract or a published lecture, review, or thesis). At the time of its submission to PJBMB it should neither be under consideration for publication elsewhere nor will it be reproduced after its publication in any other journal. Any co-authors must have agreed with the contents of the publication including the institution where the work was carried out. All authors should have agreed to the automatic transfer of copyright to the Editor-in-Chief of PJBMB.</p> <p>Since 1968, the Pakistan Journal of Biochemistry and Molecular Biology (PJBMB) has been consistently published as the official publication of the Pakistan Society of Biochemistry and Molecular Biology. As a result, it stands as one of the nation’s most longstanding scholarly periodicals.</p> <p>Since 2010, volumes of PJBMB is being published online (ISSN E 2788-4147). Recently, PJBMB has established online journal publishing with the help of "Open Journal Systems" (OJS). The OJS is an open-source software application for managing and publishing scholarly journals.</p> <p>PJBMB volumes published since 2018 to date are available online at pjbmb.com. Whereas, volumes published during 2010-2017 can be accessed at www.pjbmb.org.pk.</p> </div> </div> </div> en-US exeditor.pjbmb@gmail.com (Prof. Dr. M. Kamran Azim) mkamranazim@yahoo.co.uk (Dr. M. Kamran Azim) Tue, 24 Jun 2025 07:35:07 +0000 OJS 3.2.1.3 http://blogs.law.harvard.edu/tech/rss 60 Timely Reporting of Critical Alerts; a Key Performance Indicator in Clinical Laboratories http://www.pjbmb.com/index.php/pjbmb/article/view/132 <p>Timely reporting of critical laboratory results is crucial for patient safety and clinical decision-making. Critical alerts, also known as panic values, necessitate immediate communication with clinicians to enable prompt intervention. This study evaluates the frequency and timeliness of critical alert reporting as a key performance indicator in a specialized kidney institute's clinical laboratory. A retrospective cross-sectional study was conducted at the Multan Institute of Kidney Diseases over 2.5 years (April 2021–October 2023). Data on critical alerts were extracted from the Laboratory Information System (LIS) and analyzed using Microsoft Excel. The study assessed the incidence of critical values across different lab sections and evaluated adherence to the 30-minute reporting benchmark. A total of 1,015,285 tests were processed, with 18,540 (2.5%) yielding critical values. The majority of alerts originated from chemical pathology (83.4%), followed by hematology (16.6%). Despite a stringent reporting target of 30 minutes, the compliance rate was high, with hematology achieving 99.82% and chemical pathology 96.72% of timely notifications. Serum electrolytes, creatinine, and complete blood count (CBC) tests were the most frequently flagged parameters. Notably, the outpatient department (OPD) accounted for the highest number of critical alerts due to higher test requisition rates. The study highlights the effectiveness of structured protocols and digital tools in enhancing the timeliness of critical result reporting. While the laboratory demonstrated high compliance with CAP-recommended reporting timeframes, occasional delays were attributed to system workload and recipient response time. Continuous staff training and the integration of automated alert systems could further optimize reporting efficiency and patient care.</p> Muhammad Zubair, Aroofa Tasneem , Sahrish Haji, Umar Siddique Copyright (c) 2025 PAKISTAN JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY http://www.pjbmb.com/index.php/pjbmb/article/view/132 Tue, 24 Jun 2025 00:00:00 +0000